男，理学博士，教授，博士生导师，生命科学学院植物生物学系主任，江苏省优秀青年基金获得者，南京农业大学高层次引进人才，入选第五批南京农业大学钟山学术新秀。

联系方式：mjchen@njau.edu.cn

地址：南京农业大学生科楼C2001

ResearchGate: https://www.researchgate.net/profile/Mingjia_Chen

一. 研究方向：

1. 高等植物核酸代谢相关基因挖掘

2. RNA表观遗传修饰介导植物抗逆机制阐释

3. RNA新型化学修饰功能解析

欢迎对以上研究方向感兴趣并有志于从事相关科学研究的同学报考本人研究生。优秀者有机会前往德国开展科研合作交流、访学。

招生方向：学硕，071001 植物学 09（全日制）植物逆境生理与分子生物学；专硕，086001 生物技术与工程 01（全日制）植物生物技术；博士，071001 植物学（2）植物抗逆分子与遗传改良。

因工作需要，课题组近期计划招聘钟山青年研究员（年薪不少于23万元，业绩优秀者可达25-30万元及以上）1-2名, 要求:

1.已经（或者即将）获得植物生物化学、分子生物学、遗传学等相关领域博士学位，熟练掌握分子生物学和生物化学等研究技术，以第一作者发表过领域内高水平SCI论文。
2.年龄一般不超过35岁；工作勤奋，具有良好团队合作精神和一定的领导力；对科学探索有浓厚兴趣，有较强的独立科研工作和英文写作能力。
3.具有RNA生物学及表观遗传学相关研究背景者，具有海外经历者优先考虑。

请应聘者将材料，包括个人简历，研究工作经历，发表文章等材料通过电子邮件发送至mjchen@njau.edu.cn (请注明“南农博士后申请”)。

二. 受教育和工作经历：

2025/01 - 今 南京农业大学，生命科学学院，教授，博导

2024/09 - 2024/12 南京农业大学，生命科学学院，副教授，博导（破格）

2018/12 - 2024/08 南京农业大学，生命科学学院，副教授，硕导

2018/01 - 2019/11 德国汉诺威大学，植物营养研究所，Junior Group Leader

2016/10 - 2017/12 德国汉诺威大学，植物营养研究所，博士后

2014/10 - 2016/09 德国汉诺威大学，植物营养研究所，博士

2012/09 - 2014/09 德国柏林自由大学，生物学系，博士

2009/09 - 2012/08 中国农业科学院，植物保护研究所，硕士

教学情况

主讲本科生课程《文献检索与科技论文写作》、《基因工程原理（双语）》、《植物生理学》、《植物生理学实验》、《免疫学》、《免疫学实验》

科研情况

一. 主要科研项目

1. 国家自然科学基金专项项目 2024 - 2027（参与）

2. 国家自然科学基金面上项目 2024 - 2027（主持）

3. 江苏省自然科学基金优秀青年基金 2023-2026 （主持）

4. 国际遗传工程和生物技术中心（ICGEB）联合项目 2021-2023 （主持）

5. 中央高校基本科研业务费 （新疆联合基金；引导专项） 2021-2023 （主持）

6. 国家自然科学基金青年基金项目 2020 - 2022（主持，已结题）

7. 江苏省自然科学基金 2019 – 2022（主持，已结题）

8. 中央高校基本科研业务费 2020-2021（主持，已结题）

9. 南京农业大学高层次引进人才启动基金（主持）

二. 学术兼职

Nature Plants, Developmental Cell, Advanced Science, EMBO reports, iScience, Journal of Experimental Botany, Communications Biology 等SCI期刊审稿人，德国国家科研基金会（German Research Foundation）基金评审。

三. 代表性学术论文

1. Chunyan Meng, Xiaoyan Shi, Wenting Guo, Xing Jian, Jie Zhao, Yan Wen, Ruiqi Wang, Yu Li, Sha Xu, Haitao Chen, Jiayu Zhang*, Mingjia Chen*, Hao Chen*, Baixing Wu*. (2025) Structural analysis of ASCH domain-containing proteins and their implications for nucleotide processing. Structure https://doi.org/10.1016/j.str.2025.08.015  (* Corresponding Author) IF_5years: 4.5

2. Jie Zhao, Huijie Liu, Tingting Li, Yanpeng Li, Meiqi Wang, Huiting Ci, Yanwu Lu, Changhua Zhu, Lijun Gan, Shiguo Chen, Wenbiao Shen, Fadi Chen, Huatao Chen, Xiaoguang Chen, Zhenxing Wang*, Wenxian Liu*, Mingjia Chen*. (2025) N4-acetylcytidine mRNA modification regulates photosynthesis in plants. New Phytologist https://doi.org/10.1111/nph.70323 IF_5years: 10.3

3. Lijun Gan*, Manman Wei, Shanqi Cao, Hui Zhang, Xuechun Wang, Mingjia Chen, Na Yang, Changhua Zhu, Yi Li*. (2025) Overexpression of housekeeping gene FveIPT2 enhances anthocyanin and terpenoid accumulation in strawberry fruits with minimal impact on plant growth and development. Horticulture Research uhaf130, https://doi.org/10.1093/hr/uhaf130 IF_5years: 9.1

4. Ziyi Zhao, Shuang Zeng, Huijie Liu, Mingjia Chen, Dongdong Li*, Kunsong Chen. (2025) Dynamic abundances of m7G, m5C and m1A mRNA modifications are associated with tomato fruit quality following harvest. Postharvest Biology and Technology 225:113522 IF_5years: 6.9

5. Mingjia Chen, Hui Zhang, Shanqi Cao, Mengying Song, Dexing Yin, Xi Wang, Manman Wei, Changhua Zhu, Na Yang, Lijun Gan*. (2025) Cytokinin negatively regulates tomato fruit ripening by influencing the ethylene pathway. Plant Cell Reports 44:41 https://doi.org/10.1007/s00299-025-03430-z IF_5years: 5.3

6. Zhao, Jie^#, Tengfeng Yang^#, Peng Liu, Huijie Liu, Hui Zhang, Sichao Guo, Xiaoye Liu, Xiaoguang Chen, Mingjia Chen*. (2024) Genome-wide identification of the soybean AlkB homologue gene family and functional characterization of GmALKBH10Bs as RNA m⁶A demethylases and expression patterns under abiotic stress. Plants 13: 2491. https://doi.org/10.3390/plants13172491 (* Corresponding Author) IF_5years: 4.4

7. Peng Liu ^#, Huijie Liu ^#, Jie Zhao ^#, Tengfeng Yang, Sichao Guo, Luo Chang, Tianyun Xiao, Anjie Xu, Xiaoye Liu, Changhua Zhu, Lijun Gan, Mingjia Chen*. (2024) Genome-wide identification and functional analysis of mRNA m6A writers in soybean under abiotic stress. Frontiers in Plant Science 15, 1146 (* Corresponding Author) IF_5years: 5.3

8. Juan Liu ^#, Mingpu Tan^#, Yingying Zhang, Jie Zhao, Huijie Liu, Peng Liu, Wenna Meng, Anping Ding, Zengxu Xiang*, Mingjia Chen*. (2024) Dissecting the roles of increased mRNA m⁶A methylation in autotetraploidization in Stevia rebaudiana. Plant Growth Regulation (* Corresponding Author) https://doi.org/10.1007/s10725-024-01199-x IF: 3.5

9. Wenlei Wang^#, Huijie Liu^#, Feifei Wang, Xiaoye Liu, Yu Sun, Jie Zhao, Changhua Zhu, Lijun Gan, Jinping Yu, Claus-Peter Witte, Mingjia Chen*. (2023) N4-acetylation of cytidine in (m)RNA plays essential roles in plants. The Plant Cell 35:3739-3756 (* Corresponding Author). https://doi.org/10.1093/plcell/koad189 IF_5years: 12.796

10. Shangyu Gao ^#, Yu Sun ^#, Xiaoguang Chen, Changhua Zhu, Xiaoye Liu, Wenlei Wang, Lijun Gan, Yanwu Lu, Frank Schaarschmidt, Marco Herde, Claus-Peter Witte*, Mingjia Chen*. (2023) Pyrimidine catabolism is required to prevent the accumulation of 5-methyluridine in RNA. Nucleic Acids Research 51: 7451-7464 (* Corresponding Author). https://doi.org/10.1093/nar/gkad529 IF: 19.16

11. Jinjiao Zuo^#, Yanan Cao^#, Zhisheng Wang, Abid Ullah Shah, Wenlei Wang, Chen Dai, Mingjia Chen, Jian Lin*, Qian Yang*. (2021) The mechanism of antigen-presentation of avian bone marrowed dendritic cells suppressed by infectious bronchitis virus. Genomics 113: 1719-1732 IF: 6.205

12. Changhua Zhu^#, Xiaoye Liu^#, Wenlei Wang, Xiaoguang Chen, Shangyu Gao, Meng Qian, Na Yang, Yifeng Xu, Mingjia Chen* (2021) Plant sample preparation for nucleoside/nucleotide content measurement with an HPLC-MS/MS. Journal of Visualized Experiments doi: 10.3791/61956, (* Corresponding Author) IF_5years: 1.54

13. Mingjia Chen* and Claus-Peter Witte* (2020) A kinase and a glycosylase catabolize pseudouridine in the peroxisome to prevent toxic pseudouridine monophosphate accumulation. The Plant Cell 32: 722-739 (* Corresponding Author)  IF_5years: 12.796

14. Mingjia Chen* and Claus-Peter Witte (2019) Functions and dynamics of methylation in eukaryotic mRNA. In: Jurga S., Barciszewski J. (eds) The DNA, RNA, and Histone Methylomes. RNA Technologies. Springer Nature, Berlin, Heidelberg, 333-351 (* Corresponding Author) DOI: 10.1007/978-3-030-14792-1_13

15. Mingjia Chen, Mounashree J. Urs, Ismael Sánchez-González, Monilola A. Olayioye, Marco Herde, Claus-Peter Witte*. (2018) m⁶A RNA degradation products are catabolized by an evolutionarily conserved N⁶-methyl-AMP deaminase in plant and mammalian cells. The Plant Cell 30: 1511-1522  IF_5years: 12.796

Highlighted in Plant Cell by the Editors: "The Story Continues: Following the Fate of m⁶A Marks in the Eukaryotic Transcriptome", Plant cell 30: 1385-1386.

16. Mingjia Chen, Marco Herde, Claus-Peter Witte*. (2016) Of the nine cytidine deaminase-like genes in Arabidopsis, eight are pseudogenes and only one is required to maintain pyrimidine homeostasis in vivo. Plant Physiology 171: 799-809 IF_5years: 9.115

17. Mingjia Chen, Caizhi Zhang, Qian Zi, Dewen Qiu, Wenxian Liu, Hongmei Zeng*. (2014) A novel elicitor identified from Magnaporthe oryzae triggers defense responses in tobacco and rice. Plant Cell Reports 33: 1865-1879  IF_5years: 5.004

18. Mingjia Chen, Hongmei Zeng*, Dewen Qiu, Lihua Guo, Xiufen Yang, Huaixing Shi, Tingting Zhou, Jing Zhao. (2012) Purification and characterization of a novel hypersensitive response-inducing elicitor from Magnaporthe oryzae that triggers defense response in rice. PLoS ONE 7: e37654  IF_5years: 3.34

19. Jing Zhao, Lihua Guo*, Hongmei Zeng, Xiufen Yang, Jingjing Yuan, Huaixing Shi, Yehui Xiong, Mingjia Chen, Lei Han, Dewen Qiu*. (2012) Purification and characterization of a novel antimicrobial peptide from Brevibacillus laterosporus strain A60. Peptides 33: 206-211 IF_5years: 2.69

20. Huaixing Shi, Hongmei Zeng*, Xiufen Yang, Jing Zhao, Mingjia Chen, Dewen Qiu*. (2012) An insecticidal protein from Xenorhabdus ehlersii triggers prophenoloxidase activation and hemocyte decrease in Galleria mellonella. Current Microbiology 64: 604-610 IF_5years: 1.67

21. Tingting Zhou, Hongmei Zeng*, Dewen Qiu, Xiufen Yang, Bingnan Wang, Mingjia Chen, Lihua Guo, Shuangchao Wang. (2011) Global transcriptional responses of Bacillus subtilis to xenocoumacin 1. Journal of Applied Microbiology 111: 652-662 IF_5years: 2.81