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王卉 / 副教授

个人简介

Faculty Appointment
2007.6 - 2013.3    Lecturer, College of Life Sciences, Nanjing Agricultural University
2013.4 - present   Associate Professor, College of Life Sciences, Nanjing Agricultural University
2013.8-2014.7   Visiting Scholar,Perelman School of Medicine, University of Pennsylvania, U.S.A

Memberships in Professional Societies
2015-present   Chinese Society of Biochemistry and Molecular Biology, Committee member


教学情况

Teaching
Molecular biology
Biochemistry
Biochemical technology principle and method
Microbiology experiment
Advanced microbiology
Advanced molecular biology

Book Chapters
Biao shen, Hui Wang, Jian Kong, et al. “Differentiation of microorganism”, Microbial physiology, China Agriculture Press, 2009


科研情况

Peer Reviewed Publications

  Hui Wang#, Zengtao Zhong#, Tao Cai, Shunpeng Li and Jun Zhu*. Heterologous Overexpression of Quorum Sensing Regulators to Study Cell-Density Dependent Phenotypes in a Symbiotic Plant Bacterium Mesorhizobium huakuii. Arch. Microbiol. 182(6):520-525, 2004
  Yijing Gao, Zengtao Zhong, Kejing Sun, Hui Wang and Jun Zhu*. The quorum-sensing system in a plant bacterium Mesorhizobium huakuii affects growth rate and symbiotic nodulation. Plant Soil. 286:53-60, 2006
 Hui Wang#, Tao Cai#, Mengwei Weng, Jing Zhou, Huijuan Cao, Zengtao Zhong and Jun Zhu*. Conditional production of acyl-homoserine lactone-type quorum-sensing signals in clinical isolates of enterobacteria. J. Med. Microbiol. 55(Pt 12):1751-1753, 2006
 Wang Yunduan#, Wang Hui#, Cui Zhigang, Chen Haili, Zhong Zengtao, Kan Biao* and Zhu Jun*. The prevalence of functional quorum-sensing systems in recently emerged Vibrio cholerae toxigenic strains. Environ. Microbiol. Rep., 3(2):218-222, 2011 (Co-first author)  (IF 3.232)
  Hui Wang#, Shusu Chen#, Juan Zhang, Francesca P. Rothenbacher, Tiantian Jiang, Biao Kan, Zengtao Zhong and Jun Zhu*. Catalases Promote Resistance of Oxidative Stress in Vibrio cholera. PLoS One, 7(12), 2012  (IF 3.73)
  Sushu Chen#, Hui Wang#, David S. Katzianer, Zengtao Zhong and Jun Zhu*. LysR family activator-regulated major facilitator superfamily transporters are involved in Vibrio cholerae antimicrobial compound resistance and intestinal colonization. Int. J. Antimicrob Agents. 41(2013):188-192, 2013 (Co-first author)  (IF 4.259)
  Menghua Yang, Zhi Liu, Chambers Hughes, Andrew M. Stern, Hui Wang, Zengtao Zhong, Biao Kan, William Fenical and Jun Zhu*. Bile salt-induced intermolecular disulfide bond formation activates Vibrio cholerae virulence. Proc. Natl. Acad. Sci. U.S.A. 110(6): 2348–2353, 2013  (IF 9.681)
  Bin Pei, Yuning Wang, David S. Katzianer, Hui Wang, Hui Wu, Zengtao Zhong and Jun Zhu*. The role of a TehA homolog in Vibrio cholerae antibiotic resistance and intestinal colonization. Can. J. Microbiol. 59(2):136-139,2013  (IF 1.363)
  Yunduan Wang#, Hui Wang#, Weili Liang, Amanda J. Hay, Zengtao Zhong, Biao Kan*, Jun Zhu*. Quorum sensing regulatory cascades control Vibrio fluvialis pathogenesis. J Bacteriol. 196(16):3583-3589, 2013 (Co-first author) (IF 2.688)
  Jun Ling, Huiming Zheng, David S. Katzianer, Hui Wang, Zengtao Zhong, Jun Zhu*. Applying reversible mutations of nodulation and nitrogen-fixation genes to study social cheating in Rhizobium etli-legume interaction. PLoS One. 8(7): e70138, 2013
  Zhenyu Liu, Yuning Wang, Shengyan Liu, Ying Sheng, Karl-Gustav Rueggeberg, Hui Wang, Jie Li, Frank X. Gu, Zengtao Zhong, Biao Kan*, Jun Zhu*. Vibrio cholera Represses Polysaccharide Synthesis To Promote Motility in Mucosa. Infection and Immunity. 83(3):1114-1121, 2015
  David Katzianer#, Hui Wang#, Ryan Carey, and Jun Zhu*. “Quorum Non-Sensing”: Social Cheating and Deception in Vibrio cholerae. Appl Environ Microbiol. 81(11):3856-3862, 2015 (Co-first author) (2014 IF 3.668)
  Ying Sheng, Fenxia Fan, Owen Jensen, Zengtao Zhong, Biao Kan, Hui Wang* and Jun Zhu*. Dual zinc transporter systems in Vibrio cholerae promote competitive advantages over gut microbiome. Infection and Immunity. 83(10):3902-3908, 2015.  (Co-Corresponding author)
  Wang Y#, Wang H#, Hay AJ, Zhong Z, Zhu J*, Kan B*. Functional RelBE-Family Toxin-Antitoxin Pairs Affect Biofilm Maturation and Intestine Colonization in Vibrio cholerae. PLoS ONE. 10(8): e0135696, 2015.  (Co-first author)
  Zhi Liu, Hui Wang, Zhigang Zhou, Nawar Naseer, Fu Xiang, Biao Kan, Mark Goulian, Jun Zhu. Differential Thiol-Based Switches Jump-Start Vibrio cholerae Pathogenesis. Cell Reports. 14:1–8, 2016. (Co-first author)
  Yue Zhao, Logan M. Nickels, Hui Wang, Jun Ling, Zengtao Zhong, Jun Zhu. OxyR-regulated catalase activity is critical for oxidative stress resistance, nodulation and nitrogen fixation in Azorhizobium caulinodans. FEMS Microbiology Letters. 2016
  Zhi Liu#, Hui Wang#, Zhigang Zhou, Ying Sheng, Nawar Naseer, Biao Kan, Jun Zhu*. Thiol-based switch mechanism of virulence regulator AphB modulates oxidative stress response in Vibrio cholera. Mol. Microbiology. 2016
  Jun Ling#, Hui Wang#, Ping Wu, Tao Li, Yu Tang, Zhi Liu, Nawar Naseer, Huiming Zheng, Catherine Masson-Boivin, Zengtao Zhong, Jun Zhu*. Nodulation-Inducing Plant Compounds Enhance Horizontal Gene Transfer of Symbiosis Islands and Broaden Rhizobial Host-Range Specificity. Proc. Natl. Aca. Sci. USA. Under review.


Research Support

  The National Basic Research Program of China (973 Program)     Role: Subtopic PI
Adaptive evolution mechanism of the key biological characteristics of important pathogen (2015CB554200). Subtopic: Epigenetics modification and adaptive evolution of pathogen (2015CB554203), 2015-2020
  Natural Sciences Foundation of China      Role: PI
“Thiol-based switches of AphB on ROS and RNS resistance and virulence in Vibrio cholerae”(81371763), 01/01/14-12/31/17
  Natural Sciences Foundation of China      Role: PI
“Diversity of Vibrio Cholerae quorum sensing regulator HapR and its influence on infection” (30900036), 01/01/10-12/31/12
  973 Project    
“Molecular mechanism of nitrogen fixation in Rhizobium”, 1/1/2010-01/08/2014
  Natural Sciences Foundation of China Young Scientist Award
“Molecular mechanism of the degradation of imazethapyr by Pseudomonas sp. IM-4”, 01/01/2010-12/01/2012
  Natural Sciences Foundation of China Young Scientist Award
“Difference of Quorum-sensing system in Mesorhizobium huakuii and its effects on signal interaction between bacteria and hosts”, 01/01/2009-12/01/2011
  Natural Sciences Foundation of China Young Scientist Award
“Difference of Quorum-sensing system in Mesorhizobium huakuii and its effects on signal interaction between bacteria and hosts”,
  Natural Sciences Foundation of China
“Quorum-sensing regulation in the inter action between Mesorhiozobium Tianshanense and its hosts”, 01/01/2006-12/01/2008 

Conference

  2016.4, The 7th Vibrio Conference, Roscoff, France
  2014.10, The 3rd Asian Conference on Plant-Microbe Symbiosis and Nitrogen Fixation (3APMNF), Chengdu, China
  2014.5, The 23rd Annual Philadelphia Infection & Immunity Forum, Philadelphia, U.S.A
  2013.11, Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research (MARCE), Turf Valley Resort and Conference Center, Ellicott City, U.S.A
  2011.11, Annual conference of Agricultural Environmental Microbial Engineering Key Laboratory of Agricultural Department, Nanjing
  2010.9, Annual conference of Jiangsu Society for Microbiology, Zhenjiang
  2008.11, Annual conference of Agricultural Environmental Microbial Engineering Key Laboratory of Agricultural Department, Nanjing