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张炜 / 教授

个人简介

简介:1970年10月出生。1992年毕业于兰州大学生物系,获理学学士学位。1995年毕业于华东师范大学生物系,获理学硕士学位。1998年毕业于复旦大学遗传学研究所,获理学博士学位。1998年至2003年在美国加州大学洛杉矶分校(UCLA)、德克萨斯州立大学西南医学中心(UT Southwestern Medical Center)从事博士后研究工作。2003年至今在南京农业大学生命科学学院任教授、博士生导师。
联系方式:电话: 86-25-84399572         E-mail: wzhang@njau.edu.cn


教学情况

主讲本科生《基础生物化学》和研究生《现代生物化学》、《生物化学研究进展》等课程。教育部生物技术与生物工程教学指导委员会委员。


科研情况

主持的科研项目:
1)2005年国家自然科学基金青年项目:盐胁迫下耐盐及盐敏感粳稻的质膜蛋白质组学研究。
2)2008年国家自然科学基金面上项目:水稻线粒体热激蛋白70调节盐胁迫诱导细胞程序性死亡的功能分析。
3)2012年国家自然科学基金面上项目:叶绿体细胞色素f在水稻中诱导细胞程序性死亡的分子机制。
4)2016年国家自然科学基金面上项目:化学修饰单壁碳纳米管用于莱茵衣藻光合产氢及相关机理研究。
5)2007年国家高技术研究发展计划(863计划)课题:水稻线粒体HSP70调控细胞程序性死亡及其在抗逆中的应用。
6)2004年江苏省基础研究计划创新人才基金资助项目:盐胁迫下水稻质膜蛋白质组学研究。
7)2013年江苏省科技支撑计划农业项目:高溶菌酶高蛋白酵母饲料关键技术研究。
8)2005年教育部新世纪优秀人才。
9)2010、2013年江苏省333工程第三层次培养对象。
近期发表SCI论文(*通讯作者):
1) Xi Chen, Jiyu Li, Lihua Wang, Gang Ma & Wei Zhang*. (2016) A mutagenic study identifying critical residues for the structure and function of rice manganese transporter OsMTP8.1. Scientific Reports 6, 32073; doi:10.1038/srep32073.
2) Jing Cui, Bing Chen, Hongjuan Wang, Yue Han, Xi Chen*, Wei Zhang*. (2016) Glucosidase II β-subunit, a novel substrate for caspase-3-like activity in rice, plays as a molecular switch between autophagy and programmed cell death. Scientific Reports. 6, 31764; doi:10.1038/srep31764.
3) Hongjuan Wang, Xiaonan Zhu, Huan Li, Jing Cui, Cheng Liu, Xi Chen, Wei Zhang*. (2014) Induction ofcaspase-3-like activity in rice following release of cytochrome f from the chloroplast into the cytoplasm and subsequent interaction with the ubiquitin-proteasome system. Scientific Reports. 4, 5989; DOI: 10.1038/srep05989.
4) Liu C, Han Y, Chen X, Zhang W*. (2014) Structure-function relationship of SW-AT-1, a serpin-type trypsin inhibitor in silkworm. PLoS One. 9(6): e99013.
5) Xiao-Yu Liu, Huan Li and Wei Zhang*. (2014) The lectin from Musa paradisiaca binds with the capsid protein of tobacco mosaic virus and prevents viral infection. Biotechnology & Biotechnological Equipment. DOI: 10.1080/13102818.2014.925317.
6) Yu Chen, Xi Chen, Hongjuan Wang, Yiqun Bao, Wei Zhang*. (2014) Examination of the leaf proteome during flooding stress and the induction of programmed cell death in maize. Proteome Science. doi:10.1186/1477-5956-12-33.
7) Yu Zou; Xiaoyu Liu; Qing Wang; Yu Chen; Cheng Liu; Yang Qiu; Wei Zhang*. (2014) OsRPK1, a Novel Leucine-Rich Repeat Receptor-like Kinase, Negatively Regulates Polar Auxin Transport and Root Development in Rice. BBA General Subjects. DOI:10.1016/j.bbagen.2014.01.003.
8) Yajing Xie, Wei Zhang*. (2012) Antihypertensive activity of Rosa rugosa Thunb. flowers: Angiotensin I converting enzyme inhibitor. Journal of Ethnopharmacology. 144: 562–566.
9) Yaocheng Qi, Hongjuan Wang, Yu Zou, Cheng Liu, Yanqi Liu, Ying Wang, and Wei Zhang*. (2011) Over-expression of Mitochondrial Heat Shock Protein 70 Suppresses Programmed Cell Death in Rice. FEBS Lett. 585(1): 231-239.
10) Yanwei Cheng, Yaocheng Qi, Qian Zhu, Xi Chen, Ning Wang, Xin Zhao, Haiyan Chen, Xiangju Cui, Langlai Xu, and Wei Zhang*. (2009) New Changes in the Plasma Membrane Associated Proteome of Rice Roots under Salt Stress. Proteomics 9: 3100-3114.
11) Xi Chen, Ying Wang, Jianyou Li, Ailiang Jiang, Yanwei Cheng, Wei Zhang*. (2009) Mitochondrial proteome during salt stress-induced programmed cell death in rice. Plant Physiol. Biochem. 47: 407-415.
12) Ai-liang Jiang, Yanwei Cheng, Jianyou Li, Wei Zhang*. (2008) A zinc-dependent nuclear endonuclease is responsible for DNA laddering during salt-induced programmed cell death in root tip cells of rice. J. Plant Physiol. 165: 1134-1141.
13) Xi Chen, Wei Zhang*, Yajing Xie, Wei Lu, Rongxian Zhang. (2007) Comparative proteomics of thylakoid membrane from a chlorophyll b-less rice mutant and its wild type. Plant Sci. 173: 397-407.
14) Jianyou Li, Ailiang Jiang, Wei Zhang*. (2007) Salt stress-induced programmed cell death in rice root tip cells. J. Integr. Plant Biol. 49(4): 481- 486.
15) Jian-You Li, Ai-Liang Jiang, Hai-Yan Chen, Ying Wang, Wei Zhang*. (2007) Lanthanum prevents salt stress-induced programmed cell death in rice root tip cells by controlling early induction events. J. Integr. Plant Biol. 49(7): 1024-1031.