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赵明文 / 教授

个人简介

赵明文,男, 2003年毕业于南京农业大学生命科学学院微生物学系,获得理学博士学位。现任南京农业大学生命科学学院教授,博士生导师,国家食用菌产业体系《优质栽培生理》岗位科学家。并担任中国食用菌协会理事,中国农学会食用菌分会理事,《菌物学报》编委。入选江苏省人事厅“333工程”优秀中青年学术带头人培养计划和江苏省教育厅“青蓝工程”优秀中青年学术骨干教师。主要从事食药用真菌的遗传育种和食用菌工厂化栽培相关的研究工作。在真菌的分子遗传、食用菌的遗传育种和工厂化栽培等领域形成了自己的研究特色。主持国家自然科学基金4项,江苏省自然科学基金创新人才项目1项,江苏省农业科技支撑项目2项,上海市农委重点攻关项目子项目3项,南京农业大学青年基金1项。以第一作者和通讯作者发表相关论文40多篇,其中SCI论文30多篇,论著2部,参与获得上海市科技进步二等奖1项。
邮箱:mwzhao@njau.edu.cn


教学情况

承担本科生“微生物学”和“食用菌生产技术”两门课程的教学任务。


科研情况

近期发表的论文: 
2017

1) Liu Y. N., X. X. Lu, C. Dai, Y. P. Lu, A. Ren, L. Shi, J. Zhu, A. L. Jiang, H. S. Yu, M. W. Zhao*, Phospholipase D and phosphatidic acid mediate heat stress induced secondary metabolism in Ganoderma lucidum, Environmental Microbiology, 2017, DOI: 10.1111/1462-2920.13928,  *corresponding author
2) Liu Y. N., T. J. Zhang, X. X. Lu, B. L. Ma, A. Ren, L. Shi, A. L. Jiang, H. S. Yu, M. W. Zhao*, Membrane fluidity is involved in the regulation of heat stress induced secondary metabolism in Ganoderma lucidum, Environmental Microbiology, 2017, 19(4): 1653–1668 ,  *corresponding author
3) Ren A.※, R. Liu※, Z. G. Miao※, X. Zhang, P. F. Cao, T. X. Chen, C. Y. Li, L. Shi, A. L. Jiang, M. W. Zhao*, Hydrogen-rich water regulates effects of ROS balance on morphology, growth and secondary metabolism via glutathione peroxidase in Ganoderma lucidum, Environmental Microbiology, 2017, 19(2): 566–583, *corresponding author
4) Wu C. G., J. L. Tian, R. Liu, P. F. Cao, T. J. Zhang, A. Ren, L. Shi, M. W. Zhao*, Ornithine decarboxylase mediated production of putrescine influences ganoderic acid biosynthesis via the regulation of ROS in Ganoderma lucidum, Applied and Environmental Microbiology, 2017, 83(20): e01289-17  *corresponding author
5) Zhang G., Z. H. Sun, A. Ren, L. Shi, D. K. Shi, X. B. Li, M. W. Zhao*, The mitogen-activated protein kinase GlSlt2 regulates fungal growth, fruiting body development, cell wall integrity, oxidative stress and ganoderic acid biosynthesis in Ganoderma lucidum, Fungal Genetics and Biology, 2017, 104, 6-15    *corresponding author
6) Shi D. K., J. Zhu, Z. H. Sun, G. Zhang, R. Liu, T. J. Zhang, S. L. Wang, A. Ren,  M. W. Zhao*, Alternative oxidase impacts ganoderic acid biosynthesis by regulating intracellular ROS level in Ganoderma lucidum, Microbiology-SGM, 2017, DOI: 10.1099/mic.0.000527  *corresponding author
7) Shi L., T. J. Zhang, C. Xu, A. Ren, A. L. Jiang, H. S. Yu, M. W. Zhao*, Development of a dual promoter-mediated gene silencing system in Flammulina velutipes, Mycoscience, 2017, 58, 181-187  *corresponding author
8) Shi L., C. Xu, D.D. Chen, T. J. Zhang, A. Ren, M. W. Zhao*, Highly efficient liposome-mediated transformation system for the basidiomycetous fungus Flammulina velutipes, The Journal of General and Applied Microbiology, 2017, 63, 179–185  *corresponding author
9) Cao P. F., C.G. Wu, Z. H. Dang, L. Shi, A. L. Jiang, A. Ren*, M.W. Zhao*, Effects of exogenous salicylic acid on ganoderic acid biosynthesis and the expression of key genes in the ganoderic acid biosynthesis pathway in the Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (Agaricomycetes) International Journal of Medicinal Mushrooms, 2017, 19(1): 65–73 *corresponding author
10) Liu Y. N., X. X. Lu, A. Ren, L. Shi, A. L. Jiang, H. S. Yu, M. W. Zhao*, Identification of reference genes and analysis of heat shock protein gene expression in the Ganoderma lucidum after exposure to heat stress, International Journal of Medicinal Mushrooms, 2017, accept   *corresponding author

2016
11) Zhang X.※, A. Ren※, M. J. Li, P. F. Cao, T. X. Chen, G. Zhang, L. Shi, A. L. Jiang, M. W. Zhao*, Heat stress modulates mycelium growth, HSP expression, ganoderic acid biosynthesis and hyphal branching of Ganoderma lucidum via cytosolic Ca2+, Applied and Environmental Microbiology, 2016, 82(14): 4112-4125, *corresponding author
12) Wu F. L, G. Zhang, A. Ren, Z. H. Dang, L. Shi, A. L. Jiang, M. W. Zhao*, The pH-responsive transcription factor PacC regulates mycelial growth, fruiting body development and ganoderic acid biosynthesis in Ganoderma lucidum, Mycologia, 2016, 108(6):1104–1113 *corresponding author


2015
13) Han Q.※, F. L. Wu※, X. N. Wang, H. Qi, L. Shi, A. Ren, Q. H. Liu, M. W. Zhao* and C. M. Tang*, The bacterial lipopeptide iturins induce Verticillium dahliae cell death by affecting fungal signaling pathways and mediate plant defence responses involved in pathogen-associated molecular pattern-triggered immunity, Environmental Microbiology, 2015, 17(4), 1166–1188  *corresponding author
14) Li M. J., T. X. Chen, T. Gao, Z. G. Miao, A. L. Jiang, L. Shi, A. Ren, M. W. Zhao*, UDP-glucose pyrophosphorylase influences polysaccharide synthesis, cell wall components, and hyphal branching in Ganoderma lucidum via regulation of the balance between glucose-1-phosphate and UDP-glucose, Fungal Genetics and Biology, 2015, 82, 251-263  *corresponding author
15) Li C. Y.※, L. Shi※, D. D. Chen, A. Ren, T. Gao, M. W. Zhao*,  Functional analysis of the role of glutathione peroxidase (GPx) in the ROS signaling pathway, hyphal branching and regulation of ganoderic acid biosynthesis in Ganoderma lucidum, Fungal Genetics and Biology, 2015, 82, 168-180 *corresponding author
16) Shi L., L. Gong, X. Y. Zhang, A. Ren, T. Gao, M. W. Zhao*, Induced effect of Methyl jasmonate on hyphal growth and secondary metabolism of Ganoderma lucidum partly via ROS generated by NADPH oxidase, Fungal Genetics and Biology, 2015, 81: 201-211, *corresponding author
17) Ren J. ※, Y. Sang※, J. J. Ni, J. Tao, J. Lu, M. W. Zhao*, Y. F. Yao*, Acetylation regulates survival of Salmonella enterica Serovar Typhimurium under acid stress, Applied and Environmental Microbiology, 2015, 81:5675–5682 *corresponding author
18) Mu D. S., C. Y. Li, L. Shi, X. C. Zhang, A. Ren, M. W. Zhao*, Bioinformatic identification of potential microRNAs and their targets in Ganoderma lucidum (Higher Basidiomycetes), International Journal of Medicinal Mushrooms, 2015, 17(8): 783-797,  *corresponding author

2014
19) Mu D. S., C. Y. Li, X. C. Zhang, X. B. Li, L. Shi, A. Ren, and M. W. Zhao*, Functions of the nicotinamide adenine dinucleotide phosphate oxidase family in Ganoderma lucidum: an essential role in ganoderic acid biosynthesis regulation, hyphal branching, fruiting body development, and oxidative-stress resistance, Environmental Microbiology, 2014, 16(6), 1709–1728, *corresponding author
20) Ren A., X. B. Li, Z. G. Miao, L. Shi, A. L. Jaing, M. W. Zhao*, Transcript and metabolite alterations increase ganoderic acid content in Ganoderma lucidum using acetic acid as an inducer, Biotechnology Letters, 2014, 36:2529–2536  *corresponding author

2013
21) Ren A., M. J. Li, L. Shi, D. S. Mu, A. L. Jiang, Q. Han, M. W. Zhao*, Profiling and quantifying differential gene transcription provide insights into ganoderic acid biosynthesis in Ganoderma lucidum in response to methyl jasmonate, PLoS ONE, 2013, 8(6): e65027  *corresponding author
22) Ren A., X. Ouyang, L. Shi, A. L. Jiang, D. S. Mu, M. J. Li, Q. Han, M. W. Zhao*, Molecular characterization and expression analysis of GlHMGS, a gene encoding hydroxymethylglutaryl-CoA synthase from Ganoderma lucidum (Ling-zhi) in ganoderic acid biosynthesis pathway, World Journal of Microbiology and Biotechnology, 2013,29: 523-531,  *corresponding author
23) Fang X., L. Shi, A. Ren, A. L. Jiang, F. L. Wu , M. W. Zhao*, The cloning, characterization and functional analysis of a gene encoding an acetyl-CoA acetyltransferase involved in triterpene biosynthesis in Ganoderma lucidum, Mycoscience, 2013, 54: 100-105  *corresponding author
24) Wu F. L., L. Shi, J. Yao, A. Ren, C. Zhou, D. S. Mu, M. W. Zhao*, The cloning, characterization, and functional analysis of a gene encoding an isopentenyl diphosphate isomerase involved in triterpene biosynthesis in the Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher basidiomycetes ), International Journal of Medicinal Mushrooms, 2013, 15(3): 223–232  *corresponding author

2012
25) Mu D. S., L. Shi, A. Ren, M. J. Li, F. L. Wu, A L Jiang, M. W. Zhao*, The development and application of a multiple gene co-silencing system using endogenous URA3 as a reporter gene in Ganoderma lucidum,PLoS ONE, 2012,7(8): e43737  *corresponding author
26) Li C.H., L. Shi, Q. Han, H. L. Hu, M. W. Zhao*, C. M. Tang*, S. P. Li, Biocontrol of verticillium wilt and colonization of cotton plants by an endophytic bacterial isolate, Journal of Applied Microbiology, 2012, 113: 641--651   *corresponding author
27) Shi. L., X. Fang, M. J. Li, D. S. Mu, A. Ren, Q. Tan, M. W. Zhao*, Development of a simple and efficient transformation system for the basidiomycetous medicinal fungus Ganoderma lucidum, World Journal of Microbiology and Biotechnology, 2012, 28:283–291,  *corresponding author
28) Shi. L., L. Qin, Y. J. Xu, A. Ren, X. Fang, D. S. Mu, Q. Tan, M. W. Zhao*,  Molecular cloning, characterization, and function analysis of a mevalonate pyrophosphate decarbroxylase gene from Ganoderma lucidum, Molecular Biology Report, 2012, 39:6149–6159, *corresponding author

获奖情况:
1、《食用菌工业化生产关键技术与应用》;上海市科学技术奖二等奖;排名第六;2008.12
2、《青蓝工程优秀骨干教师》;江苏省教育厅;2006
3、江苏省“333工程”第三层次培养对象;2011